Babel, Dreamgirls and Little Miss Sunshine each earned nominations in three categories, with Notes On A Scandal, The Departed, Blood Diamond and Little Children each taking two mentions.
Most of the nominees were expected names being discussed during this awards season, such as Peter O'Toole for Venus and Helen Mirren for The Queen.
Among the less expected inclusions are indie favourites Ryan Gosling for lead actor in Half Nelson and young Abigail Breslin for Little Miss Sunshine.
Brad Pitt was overlooked for his role in Babel (although the ensemble cast was recognised) as was Venice best actor winner Ben Affleck for Hollywoodland. Two supporting actresses from Babel - Adriana Barraza and Rinko Kikuchi - will compete against one another.
The full list of nominees are:
Outstanding Performance by a Male Actor in a Leading Role
Leonardo DiCaprio, Blood Diamond
Ryan Gosling, Half Nelson
Peter O'Toole, Venus
Will Smith, The Pursuit of Happyness
Forest Whitaker, The Last King Of Scotland
Outstanding Performance by a Female Actor in a Leading Role
Penelope Cruz, Volver
Judi Dench, Notes On A Scandal
Helen Mirren, The Queen
Meryl Streep, The Devil Wears Prada
Kate Winslet, Little Children
Outstanding Performance by a Male Actor in a Supporting Role
Alan Arkin, Little Miss Sunshine
Leonardo DiCaprio, The Departed
Jackie Earle Haley, Little Children
Djimon Hounsou, Blood Diamond
Eddie Murphy, Dreamgirls
Outstanding Performance by a Female Actor in a Supporting Role
Adriana Barraza, Babel
Cate Blanchett, Notes On A Scandal
Abigail Breslin, Little Miss Sunshine
Jennifer Hudson, Dreamgirls
Rinko Kikuchi, Babel
Outstanding Performance by a Cast in a Motion Picture
Babel
Bobby
The Departed
Dreamgirls
Little Miss Sunshine
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